Jiangsu Vcare Approved to Establish "Jiangsu (Vcare) Chemical Innovative Drug Engineering Research Center"
Published Time:
2024-11-01 17:51
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Recently, the Nanjing Municipal Science and Technology Bureau announced the acceptance results of 2024 provincial-level engineering research centers and academician workstations. The"Jiangsu (Vcare) Chemical Innovative Drug Engineering Research Center", established byJiangsu Vcare Pharmatech Co., Ltd.(Jiangsu Vcare), successfully passed project acceptance.
Provincial Engineering Research Centers are key components of Jiangsu's innovation system and vital forces driving high-quality industrial development. Their mission is to promote technological innovation in Jiangsu by strengthening engineering R&D platforms, conducting R&D and technical services, developing common/key technologies, and providing mature technical processes, equipment, and products to facilitate achievement transformation and technological radiation.
During its establishment, the Center built a comprehensive integrated drug R&D platform covering drug discovery, synthesis, analysis, formulation, pharmacological screening, and clinical research. Leveraging this platform, it achieved notable outcomes including Vicagrel, VC004, and VC005—innovative drugs oriented to meeting clinical needs through differentiated solutions, now entering confirmatory clinical stages.
The Center has also cultivated professionals in drug design and clinical development, forming a high-caliber R&D team that enhances the company’s innovation and competitiveness. It will continue deepening R&D efforts to advance China’s pharmaceutical innovation.
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I. Important Progress in Innovative Drug R&D ① Submitted NDA to US FDA for anti-platelet drug Vicagrel: If approved, it may benefit ~27.6M US patients with coronary heart disease/stroke. ② Completed 1st patient enrollment in China’s Phase II trial for anti-resistant TRK inhibitor VC004: Phase I data showed ORR of 80%-90% in NTRK fusion+ solid tumors and DOR up to 24 months. ③ Completed Phase II enrollment for 2nd-gen selective JAK1 inhibitor VC005 in ankylosing spondylitis: Preliminary blinded analysis showed favorable efficacy/safety. Additionally: VC004 gel approved for clinical trials; VC005 gel initiated China Phase I for atopic dermatitis; Multiple preclinical projects advanced in cardio-cerebrovascular, oncology, and autoimmune fields.
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